Laboratory of Addiction Neuroscience

Chris Pierce, PhD, Director

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  • Most Recent Publications
  • Metabotropic glutamate receptor 5 (mGluR5) antagonists attenuate cocaine priming- and cue-induced reinstatement of cocaine seeking
  • Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking
  • Deep brain stimulation of the nucleus accumbens shell attenuates cocaine priming-induced reinstatement of drug seeking in rats
  • CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking
  • When administered into the nucleus accumbens core or shell, the NMDA receptor antagonist AP-5 reinstates cocaine-seeking behavior in the rat
  • Systemic administration of a dopamine, but not a serotonin or norepinephrine, transporter inhibitor reinstates cocaine seeking in the rat.
  • Complete index of publications...
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• About Dr. Pierce
• Lab Staff
  • Chris Pierce, Ph.D.
  • Audrey Pierce-Bancroft
  • Postdoctoral Fellows
  • Lisa Briand, Ph.D.
  • Research Associates
  • Pavel Ortinski, Ph.D.
  • Heath Donmar Schmidt, Ph.D.
  • Graduate Students
  • Fair Vassoler
  • Samantha White
  • Research Assistants
  • Rachel Shassburger
  • Undergraduates
  • Alumni

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Mission

The Pierce Laboratory of Addiction Neuroscience uses a multi-disciplinary approach to identify new treatments for cocaine addiction.

Copyright © 2010 Pierce Laboratory of Addiction Neuroscience